Antireflux esophageal stents: Do we have a winner?

Failed antireflux surgery: what have we learned from reoperations?

HYPOTHESIS Factors that lead to failures in antireflux procedures can be identified, and dealing with them at the initial operation may decrease the number of such failures. DESIGN Analysis of symptoms, 24-hour esophageal pH monitoring, manometry, upper gastrointestinal tract radiographs, and correlation with operative anatomic findings. SETTING University referral center. PATIENTS Forty-...

Do We Know What We Do not Know? A Response to Celine Bonnet

Aromatase Inhibitors for Endometriosis-Associated Infertility; Do We Have Sufficient Evidence?

Orally active aromatase inhibitors (AIs) have gained attention for treatment of infertile women with endometriosis in whom aromatase p450 is aberrantly expressed. This review aimed to critically appraise and summarize the available evidence concerning the use of AIs for management of endometriosis-associated infertility. PubMed was searched to May 2015 with the following key words: endometriosi...

What Tools Do We Have?

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How Do We Have Feelings?

For centuries, the question of how a physical structure (the brain) generates the subjective feeling of consciousness has plagued neuroscientists, physiologists, psychologists, linguists, and philosophers. This has become known as the “hard problem of consciousness” and has been the subject of many publications. Although lots of answers have been proposed, none has been completely satisfactory....